Prescription medicine (Schedule 4) for therapeutic use containing 2 per cent (2.0%) or less of other cannabinoids commonly found in cannabis (such as ∆9-THC). A schedule 4 drug under the SUSMP is Prescription Only Medicine, or Prescription Animal Remedy – Substances, the use or supply of which should be by or on the order of persons permitted by State or Territory legislation to prescribe and should be available from a pharmacist on prescription.[80]
The tricky part is that there's some evidence suggesting CBD works best for pain when combined with a little THC, says Dr. Danesh. "Depending on what type of pain you have, you might be able to do just CBD, but sometimes you need CBD and THC." This makes accessing a product that will actually help you more difficult due to different regulations in each state. In New York, where Dr. Danesh practices, for example, CBD is available over the counter. But as soon as you add THC, you need a prescription.
Stephanie, generally, I have patients take 20 to 150mg a day for sleep +/- anxiety. Start low and go slow. Know the dosages of your product. Usually 2/3 to 3/4 of the daily dose is 1-2 hours before bedtime, and the other portion is upon waking (to improve wakefulness during the day). Other factors such as stress, hormone replacement, other meds & medical conditions, etc. play a role along with individual differences. I own a compounding pharmacy, so we see a lot of unique needs. I can't give more specific advice in this forum, but there is help!
Pharmacists have since moved to metric measurements, with a drop being rounded to exactly 0.05 mL (50 μL, that is, 20 drops per milliliter) - https://en.wikipedia.org/wiki/Drop_(unit)1oz is 30 mL1000mg/30mL = 33.3 mg/mL CBD concentration20 drops * .05 mL/drop = 1mL10 drops * .05 mL/drop = .5mLyou take 33.3 mg in the morning and 16.65mg at nightI might suggest taking 50mg in the morning: 50mg / 33.3 mg/mL = 1.50 mL 30 dropstry it for a couple days and see how it helps
First, a little background. Industrial hemp was legal in the United States until Congress passed the Marihuana Tax Act in 1937. ("Some of our early presidents grew hemp," notes Sarah Lee Gossett Parrish, a cannabis industry attorney based in Oklahoma.) Nearly 80 years later, the 2014 Farm Bill took the position that states can regulate the production of hemp and, as a result, CBD. Then last year, President Trump signed a new Farm Bill that made it federally legal to grow hemp.
No restrictions and our always-free shipping mean for unparalleled access to some of the world’s best in organic CBD’s. In addition, we are proud to say that we are quite knowledgeable in the CBD field and CBD applications as opposed to many out there, just trying to sell a product. If you need help deciding which CBD line is best for your intended application, we are always happy to explain the options to your fullest understanding.
Thanks for your interest in our products. Unfortunately due to strict FDA regulations I am unable to make claims on our products based on your specific needs, I can though share our top selling products in each category. Please view the links below:http://cbdoilreview.org/product/elixinol-cbd-oil-extract-x-pen-1000mg/http://cbdoilreview.org/product/endoca-hemp-oil-drops-1500mg/http://cbdoilreview.org/product/elixinol-hemp-oil-drops-regular-300mg/http://cbdoilreview.org/product/elixinol-cbd-hemp-oil-capsules-900mg/https://cbdoilreview.org/product/vape-bright-thrive-cbd-vape-cartridge-200mg/As far as dosage goes, I would recommend reading through our page on dosing. I have attached that link below. https://cbdoilreview.org/cbd-cannabidiol/cbd-dosage/Hopefully these help.
I wanted to tell people here that CBD has been very effective for my anxiety, and helps with insomnia. For me, it was a cumulative effect, after a week of one dropper of oil, I can sleep very well at night. I feel like I am not polluting my body with commercial pharmaceuticals. I wish everyone here the best, and hope it works for you as well as it has for me. 

CBD and THC interact with our bodies in a variety of ways. One of the main ways they impact us is by mimicking and augmenting the effects of the compounds in our bodies called “endogenous cannabinoids” - so named because of their similarity to the compounds found in the cannabis plant. These “endocannabinoids” are part of a regulatory system called the “endocannabinoid system”.
I have dealt with overall muscle pain for several years and was finally diagnosed with fibromyalgia 6 months ago. Due to stomach issues, I am no longer able to take NSAIDs, and I don’t want to start down the opioid trail, so I’ve been pretty miserable. Most days I felt like I’d been hit by a truck, and by the end of a work day, I was done. Many evenings I had to use a foam roller on my neck, back, and legs before I could even think of going to bed, and just trying to sit and relax was sometimes impossible. My husband did a lot of research on CBD oil, and Medterra seemed to be a solid company with a good following. He got me a bottle of the 1,000mg tincture, and I “front-loaded” with two doses a day for the first 5 days, then went down to one 1ml dose each morning. Even though we were on a lake vacation and I was climbing in and out of the boat and bouncing around the lake, I noticed that the pain and achiness in my arms and legs was gone within the first couple of days. After a couple more days, I realized that the pain and tightness in my upper back/neck were nearly gone as well. I’m starting to get my “old” energy back, and I can focus on doing what I want to do without the pain constantly interfering. My next order will be for the 3,000mg tincture... I want to play with the dosing a bit and see if I can get some relief with lower back pain (unrelated to the fibro). If you’re dealing with muscle pain, I highly recommend giving Medterra CBD oil a try.

I thought maybe I would give CBD a try to help with some issues I have been having for quite awhile such as lower back pain, headaches, and trouble sleeping. After only two days of using 1ml morning and night of the 500mg I noticed a big change in how I felt. Now that I am almost a month into using I know that it really does work. I sleep so much better and have a far greater amount of energy every day. Also, my back pain isn’t near what it used. I feel great. I highly recommend giving this stuff a try.


Dr. Silberstein advises against obtaining a product in states in which CBD oil is not currently legal or regulated. Illegal forms of CBD oil could be spiked with artificial THC which could be very harmful to patients. Additionally, there are legal implications if you attempt to purchase it where it is currently illegal, so it is important to speak with your healthcare provider and check your local and state laws.
I am very impressed with this CBD oil. I tried other brands with lower dosage and was not really happy. This dosage seems to work great for me, I have a crunched vertebrae from a quad wreck, and the mornings have always been the worst. Within a day I was already noticing great relief. I have contacted Medterra a few times and each time they were quick to respond and very helpful. I will always do my CBD business with this company!
The hemp oil in our product contains CBD which is a LEGAL cannabinoid from hemp. It contains minuscule amounts (parts per billion) of THC that COULD show up in a drug screen. PureKana cannot guarantee that you will or will not pass a drug screen due to the amount of variables. Our products contain less than .3% THC(.02% to be exact). Drug screens vary and some can be more sensitive than others. If you have to take a drug test, it is best to not use our product.
This product was recommended for me by a friend and I couldnt be happier that we talked about this. Ive had very minor issues with anxiety from work or personal life. By taking this in the morning it really has helped me with those feelings and allowed me to enjoy my day and focus more. Its had a significant affect on my personal life and work because of it. Will be recommending to all my friends who have similar issues.
Representations regarding the efficacy and safety of CBDPure have not been evaluated by the Food and Drug Administration. The FDA only evaluates foods and drugs, not supplements like these products. These products are not intended to diagnose, prevent, treat, or cure any disease. Click here and here to find evidence of a test, analysis, research, or study describing the benefits, performance or efficacy of CBD Oil based on the expertise of relevant professionals.
^ Nadulski T, Pragst F, Weinberg G, Roser P, Schnelle M, Fronk EM, Stadelmann AM (December 2005). "Randomized, double-blind, placebo-controlled study about the effects of cannabidiol (CBD) on the pharmacokinetics of Delta9-tetrahydrocannabinol (THC) after oral application of THC verses standardized cannabis extract". Ther Drug Monit. 27 (6): 799–810. doi:10.1097/01.ftd.0000177223.19294.5c. PMID 16306858.

CBD Isolate is the purest supplement available. It’s a 99% pure CBD supplement derived from hemp oil. Despite its concentration, CBD isolate effects are similar to other CBD concentrates, and it can be used in a variety of ways. It can be consumed itself, added to foods and beverages, or vaporized. You can also add it to other CBD products to increase their potency.


CBD is an acronym for Cannabidiol (Can-a-bid-i-ol), a prominent naturally occurring class of molecules called cannabinoids found in the plant genus Cannabis Sativa L. CBD comprises up to 40% of the plant and is one of over 60 plus compounds found in cannabis. Of these compounds, CBD and THC are usually present in the highest concentrations, and are therefore the most recognized and studied. CBD is a non- psychoactive component of the plant that possesses a wide range of benefits and does not cause a high, unlike THC. Our bodies are made up of an endocannabinoid system and use cannabinoids to maintain healthy cells.

This product is not for use by or sale to persons under the age of 18. This product should be used only as directed on the label. It should not be used if you are pregnant or nursing. Consult with a physician before use if you have a serious medical condition or use prescription medications. A Doctor’s advice should be sought before using this and any supplemental dietary product. All trademarks and copyrights are property of their respective owners and not affiliated with nor do they endorse this product. These statements have not been evaluated by the FDA. This product is not intended to diagnose, treat, cure or prevent any disease. Individual weight loss results will vary. By using this site you agree to follow the Privacy Policy and all Terms & Conditions printed on this site. Void Where Prohibited By Law.
Nabiximols (brand name Sativex) is a patented medicine containing CBD and THC in equal proportions. The drug was approved by Health Canada in 2005 for prescription to treat central neuropathic pain in multiple sclerosis, and in 2007 for cancer related pain.[39][40] In New Zealand Sativex® is approved for use as an add-on treatment for symptom improvement in patients with moderate to severe spasticity due to Multiple Sclerosis who have not responded adequately to other anti-spasticity medication and who demonstrate clinically significant improvement in spasticity related symptoms during an initial trial of therapy.[41]
CBDPure oils are made with non-GMO hemp, grown in Colorado by local farmers. Our hemp oil is minimally processed by following the highest organic standards at every step of our growing, harvesting, and bottling process. When you buy a CBDPure product, you are buying the purest CBD oil from natural sources, that is 100% free of any synthetic or artificial ingredients. We test every batch of oil that we process to ensure that it meets the purity standards that we demand.

I have been using the 1000mg tincture and find that it is very effective at taming anxiety once I found the dosage that worked for me. I started small at 1 drop 3x per day because I had never used CBD before and found that 4 drops 3x a day is currently appropriate to get the results I am looking for. I am glad I found Medterra. Before making a CBS purchase, I did tons of research and felt that they were one of the best in the market. Customer Service response time was same day when I sent them a question.

By popular demand, we have also begun to carry several, high quality CBD pet products as well. For general purpose applications, we carry several, tasty tincture and oral spray options that are highly effective. Likewise, Pharma CBD capsules provide CBD purity via capsular ingestion. In addition, we have partnered with Therabis, the quality CBD maker of “Stop the Itch” and “Calm and Quiet”, the pet lovers’ ultimate go-to’s. Find these products by browsing our exclusive online inventory.
Laboratory evidence indicated that cannabidiol may reduce THC clearance, increasing plasma concentrations which may raise THC availability to receptors and enhance its effect in a dose-dependent manner.[23][24] In vitro, cannabidiol inhibited receptors affecting the activity of voltage-dependent sodium and potassium channels, which may affect neural activity.[25] A small clinical trial reported that CBD partially inhibited the CYP2C-catalyzed hydroxylation of THC to 11-OH-THC.[26]

The hemp oil in our product contains CBD which is a LEGAL cannabinoid from hemp. It contains minuscule amounts (parts per billion) of THC that COULD show up in a drug screen. PureKana cannot guarantee that you will or will not pass a drug screen due to the amount of variables. Our products contain less than .3% THC(.02% to be exact). Drug screens vary and some can be more sensitive than others. If you have to take a drug test, it is best to not use our product.


Almost completely eradicated my anxiety, which had been a severe hinderance to my life. The THC Free aspect is great for my line of work, and its no joke - I passed my last drug test. I ended up with the 1000mg strength, working my way up to 1mL from 0.5mL and 0.75mL. Also, Customer Service, when I was initially doing research, was top notch (I havent had to contact them since, but Im sure theyre still great lol).


100% organic quality is all we deal. Only select, organic growers and extraction processes are used in any product found here. Our pure CBD oil products and tinctures get to work quickly through direct, oral administration. As a capsular, daily supplement, we also have some of the best in quality CBD supplements for the easy, daily maintenance option. For those that prefer vaping, we are also proud to feature an entire line of 100% organic CBD oil vaping products including dab oils, vape oils, and even high quality vape kits.
Cutting-edge science has shown that the endocannabinoid system is dysregulated in nearly all pathological conditions. Thus, it stands to reason that “modulating endocannabinoid system activity may have therapeutic potential in almost all diseases affecting humans,” as Pal Pacher and George Kunos, scientists with the U.S. National Institutes of Health (NIH), suggested in a 2014 publication.
First, a little background. Industrial hemp was legal in the United States until Congress passed the Marihuana Tax Act in 1937. ("Some of our early presidents grew hemp," notes Sarah Lee Gossett Parrish, a cannabis industry attorney based in Oklahoma.) Nearly 80 years later, the 2014 Farm Bill took the position that states can regulate the production of hemp and, as a result, CBD. Then last year, President Trump signed a new Farm Bill that made it federally legal to grow hemp.
I have lower back pain with some arthritis and arthritis in my hands.ive recently tried CBD Oil. It really does work. I have the drops and ointment. They both work. Because of the back pain I never would have been able to go on a hike with my family. We had a lot of fun. And "No Pain", all day. I'm also Type 2 diabetic. Anxious to see what my A1C is next month. I'm a believer.
^ Hayakawa K, Mishima K, Nozako M, Ogata A, Hazekawa M, Liu AX, Fujioka M, Abe K, Hasebe N, Egashira N, Iwasaki K, Fujiwara M (March 2007). "Repeated treatment with cannabidiol but not Delta9-tetrahydrocannabinol has a neuroprotective effect without the development of tolerance". Neuropharmacology. 52 (4): 1079–87. doi:10.1016/j.neuropharm.2006.11.005. PMID 17320118.
I was so excited to try this but it hasn’t helped my back pain whatsoever. I’ve been taking it for 2 months and I’m going to give it one more month. I am taking the 500 and have doubled the dose making it 1000 mg. So disappointed.I thought in the beginning that it was giving me a little more energy. Maybe it has. I love the company. It is so easy to order and it’s shipped right away.
Hi Marilyn, I would recommend a topical lotion or salve to start for instant relief.. Maybe 250 to 300 mg tincture to see how you feel. For me, the salve took the pain in my hands away in under a minute. I didn't notice how much the tincture worked until I forgot to take on vacation. Pain that was pretty much gone but came back, I was tired, grumpy and felt horrible. It works, just need to find right product and dosage for you.
^ Jump up to: a b c d Campos AC, Moreira FA, Gomes FV, Del Bel EA, Guimarães FS (December 2012). "Multiple mechanisms involved in the large-spectrum therapeutic potential of cannabidiol in psychiatric disorders". Philosophical Transactions of the Royal Society of London. Series B, Biological Sciences (Review). 367 (1607): 3364–78. doi:10.1098/rstb.2011.0389. PMC 3481531. PMID 23108553.
When we started CBD products we were getting it in candy form from a friend. It worked really well for us adults. But for the kids it was a mess cutting hard candy is a pain. So I thought wed give the 500 mg oil a try see how they liked it. And they love it They prefer it to the candies. My daughter is not a good sleeper and she says that using the oil works better and faster than eating the candy. My sons also love it as well. There is no flavor to worry about. I give them each 4 mg under the tongue for 30 seconds and they happily go to bed and feel good the next day. I am so glad we bought this
×